exist. Granted, when you say “New Jersey” most people think of the northern part of the state (roughly everything north of I-195), with it crowding, industry, noise, traffic, trashy “reality” show and mostly, attitude. But travel south of I-195 and it’s like you changed planets. If you ask someone who grew up in the state where they’re from, and they answer “New Jersey” or just “Jersey” in all likelihood they came from north of this arbitrary dividing line. But if they came from the southern half, I can almost guarantee they’ll answer with “South Jersey”. There’s a pride-of-place that comes with the region that can’t be denied.
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Glioblastoma (GBM). GBM is the most Kendall Roy 2 and most aggressive brain cancer. It’s highly invasive, which makes complete surgical removal impossible. And because of the blood-brain barrier (BBB), it doesn’t respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called “the Whipple procedure”. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.
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