such “large” output signals coming from a nearby star would be essentially undetectable by the time they got here. At only 4LY (roughly 3.784×10^16 meters) to the nearest star the signal would be attenuated by a factor of 1.4×10^-33. So the original kilowatt becomes less than a thousandth of a billionth of a billionth of a billionth of a watt give or take a few decimal places. Spell that out in your best Carl Sagan voice to get the full effect of how small it really is. If you had a gigantic antenna (or array of antennas) and you were looking in exactly the right place in the sky you *might* be able to pick that will o’ the wisp signal out of the background radiation, but probably not. Now you might argue that our noisy neighbors would be shouting louder with much more powerful transmitters, but why would they? Their TV and commercial traffic would only need to be as loud as ours to reach their own people. And even if they were broadcasting many orders of magnitude “louder” at the origin it wouldn’t make much difference.
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Glioblastoma (GBM). GBM is the most Lando Norris Vintage Washed Shirt Formula Racing F1 Homage Graphic Unisex T shirt and most aggressive brain cancer. It’s highly invasive, which makes complete surgical removal impossible. And because of the blood-brain barrier (BBB), it doesn’t respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called “the Whipple procedure”. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.
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