erience, observation, and intention together create reality. They cannot exist without each other. None is more fundamental than the other, and none can be removed without destroying the others. Experience, observation, and intention: the grand experiment. We exist to try things, experience them, and observe the result. There is no meaning beyond that; when we are gone, all those things are gone too. We should use the little time we have to make as many experiments as possible. We have been blessed with the opportunity to experience, observe, and intend, and we should not waste it.
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Glioblastoma (GBM). GBM is the most Politics Makes Me So Horny Shirt and most aggressive brain cancer. It’s highly invasive, which makes complete surgical removal impossible. And because of the blood-brain barrier (BBB), it doesn’t respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called “the Whipple procedure”. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.
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